Reactive polymer coatings that "click"

Everything just clicks into place: Alkyne-group functionalized polymer films that are deposited from the gas phase allow spatially defined immobilization of biomolecules, such as biotin, through the 1,3-dipolar cycloaddition click reaction with azide derivatives (see scheme). Such biofunctional surfaces have applications in diagnostics and biosensors. (Figure Presented). ? 2006 Wiley-VCH Verlag GmbH & Co. KGaA.