Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH)-A Case Report
Journal
胸腔醫學
Journal Volume
29
Journal Issue
6
Pages
358
Date Issued
2014-12-01
Author(s)
Abstract
Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare pulmonary condition presenting with cough, wheezing, and obstructive ventilatory defect. The pathogenesis of the disease is diffuse hyperplasia or dysplasia of pulmonary neuroendocrine cells, multiple carcinoid tumorlets, and peribronchiolar fibrosis causing small airway obliteration. Herein, we present the case of a 70-year-old patient with this rare condition who had been treated for asthma for years, and who had a left lower lung tumor noted during follow-up chest radiography. Chest computed tomography showed a mosaic pattern of the lung parenchyma and multiple lung nodules. The pathological diagnosis of DIPNECH was made after a surgical resection of the lung nodules. The patient's symptoms remained stable with inhaled corticosteroid and bronchodilator use.
Subjects
diffuse idiopathic pulmonary neuroendocrine cell hyperplasia
neuroendocrine cells
tumorlets
carcinoid
lung neoplasm
Type
journal article