Neonatal lupus erythematosus with recurrent pancytopenia: A case report
Journal
Journal of Microbiology, Immunology and Infection
Journal Volume
35
Journal Issue
4
Pages
262-264
Date Issued
2002
Author(s)
Abstract
Neonatal lupus erythematosus is an immune-mediated disease associated with the transplacental passage of maternal autoantibodies, primarily anti-Ro (SS-A) and anti-La (SS-B). The major clinical manifestations are isolated congenital heart block and cutaneous lupus lesions. Other symptoms include hematologic and hepatic abnormalities. We report a male neonate, born to a mother with Sj?gren's syndrome, who experienced cutaneous lupus lesions and 2 episodes of pancytopenia. Both anti-Ro and anti-La antibodies were positive in infant and mother.
SDGs
Other Subjects
ampicillin; antibiotic agent; autoantibody; cefotaxime; immunoglobulin; prednisolone; steroid; article; bacterial infection; blood culture; case report; clinical feature; congenital heart block; Enterococcus faecalis; hematological parameters; hepatomegaly; human; lupus erythematosus; male; newborn; newborn disease; pancytopenia; recurrent disease; sepsis; Sjoegren syndrome; skin lupus erythematosus; skin manifestation; steroid therapy; thrombocyte transfusion; thrombocytopenia; urinary tract infection; urine culture; Antibodies, Antinuclear; Autoantibodies; Disease Transmission, Vertical; Female; Heart Block; Humans; Infant; Lupus Erythematosus, Cutaneous; Male; Pancytopenia; Pregnancy; Recurrence; Sjogren's Syndrome
Type
journal article