High prevalence of lower urinary tract dysfunction in patients with Prader–Willi syndrome
Journal
Neurourology and Urodynamics
Journal Volume
40
Journal Issue
4
Pages
1063-1068
Date Issued
2021
Author(s)
Abstract
AIMS: To report the first noninvasive urodynamic screening of lower urinary tract dysfunction (LUTD) in children, adolescents, and young adults with Prader-Willi Syndrome (PWS). METHODS: ), or elevated PVR by age. Videourodynamic study (VUDS) was performed in selected cases. RESULTS: less than 15 ml/s. Of 20 patients undergoing PVR tests 10 (50%) had elevated PVR by age ( > 6% of estimated bladder volume). In all, 17/34 (50.0%) PWS patients had at least one abnormality of the noninvasive tests. Of the three cases undergoing VUDS all showed detrusor sphincter dyssynergia. CONCLUSIONS: Half of PWS patients with/without LUTS had LUTD. Noninvasive study such as uroflowmetry and postvoid residual urine by ultrasound is recommended to all patients with PWS.
SDGs
Publisher
John Wiley and Sons Inc
Type
journal article