CONTINUOUS PHAGE SELECTION BY INTEGRATED MICROFLUIDIC CHIP
Journal
MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
ISBN
9781733419031
Date Issued
2021-01-01
Author(s)
Sie, Zong Han
Abstract
Selecting specific antibodies of the cell from the phage display library is essential for targeted therapy. However, traditional methods need a heavily manual operation and involve many devices. To tackle these limitations, we developed an integrated and low-cost microfluidic chip to promote screening efficiency. This method allows us to reduce the reaction time between phage selection cycles.
Subjects
Microfluidic chip | Phage engineering | Targeted therapy
Type
conference paper