Arsenic methylation capability, heme oxygenase-1 and NADPH quinone oxidoreductase-1 genetic polymorphisms and the stage and grade of urothelial carcinomas
Journal
Urologia internationalis
Journal Volume
80
Journal Issue
4
Pages
405
Date Issued
2008
Author(s)
Huang, Steven K
Chiu, Allen Wen-Hsiang
Huang, Yung-Kai
Chung, Chi-Jung
Tsai, Hui-Ju
Yang, Mo-Hsiung
Chen, Chien-Jen
Hsueh, Yu-Mei
Abstract
Arsenic exposure is associated with an increased risk of urothelial carcinoma (UC). To explore the distribution of the arsenic methylation capability in patients with different stages and grades of UCs, 100 UC cases were recruited between September 2002 and May 2004 for this study.
Subjects
bladder neoplasms; arsenic; methylation
SDGs
Other Subjects
arsenic; cacodylic acid; methanearsonic acid; adult; aged; article; atomic absorption spectrometry; bladder carcinoma; cancer grading; cancer staging; DNA methylation; female; gene; genetic polymorphism; genotype; high performance liquid chromatography; HO 1 gene; human; human tissue; major clinical study; male; NQO1 gene; polymerase chain reaction; priority journal; Taiwan; urinalysis; Adult; Aged; Aged, 80 and over; Analysis of Variance; Arsenic; Arsenic Poisoning; Carcinoma, Transitional Cell; Cohort Studies; DNA Methylation; Environmental Exposure; Female; Humans; Incidence; Male; Middle Aged; NADH, NADPH Oxidoreductases; Neoplasm Staging; Polymorphism, Genetic; Probability; Prognosis; Risk Assessment; Survival Analysis; Taiwan; Urinary Bladder Neoplasms
Publisher
KARGER
Type
journal article