Simultaneous osteonecrosis and osteomyelitis in a patient with cancer of the breast
Journal
Journal of Bone and Joint Surgery - Series B
Journal Volume
91
Journal Issue
9
Pages
1249-1251
Date Issued
2009
Author(s)
Abstract
Breast cancer is generally managed surgically with adjuvant agents which include hormone therapy, chemotherapy, radiotherapy and bisphosphonate therapy. However, some of these adjuvant therapies may cause adverse events, including wound infection, neutropenia, bone marrow suppression and fever. The simultaneous presentation of osteonecrosis and osteomyelitis has not previously been described in patients with breast cancer undergoing hormone therapy and chemotherapy. We report a patient with breast cancer who developed bone infarcts in both legs as well as osteomyelitis in the right distal tibia after treatment which included a modified radical mastectomy, hormone therapy and chemotherapy. Simultaneous osteonecrosis and osteomyelitis should be considered in patients with breast cancer who are receiving chemotherapy and hormone therapy who present with severe bone pain, especially if there have been infective episodes during treatment. ?2009 British Editorial Society of Bone and Joint Surgery.
SDGs
Other Subjects
alendronic acid; C reactive protein; cefazolin; docetaxel; epirubicin; fusidate sodium; gallium 67; gentamicin; goserelin; radioisotope; rifampicin; tamoxifen; abscess; adult; article; bone destruction; bone necrosis; bone pain; bone scintiscanning; breast cancer; cancer chemotherapy; case report; cellulitis; debridement; diabetes mellitus; febrile neutropenia; female; glucose blood level; hormonal therapy; human; incision; infection; intraductal carcinoma; invasive carcinoma; leg; leukocyte count; mastectomy; methicillin resistant Staphylococcus aureus infection; osteomyelitis; postprandial state; priority journal; protein blood level; skin transplantation; tibia; wound dehiscence; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Humans; Osteomyelitis; Osteonecrosis
Type
journal article