A Technology for the Measurement of Autonomic Nervous System Activity
Date Issued
2008
Date
2008
Author(s)
Li, Jain-Da
Abstract
In diabetes autonomic neuropathy may occur in Type1 and Type2. It may occur before being diagnosized and affect cardiovascular system, digestive system, Genitourinary system, sweat gland and metabolism. Autonomic neuropathy is relative to the mortality of the diabetes, so the early diagnosis and treatment are very important.his study is to measure the mean arterial pressure(MAP), dynamic HRV and the pulse wave simultaneously at four limbs by pressure receptors, and use the electrocardiogram as the reference to synchronize the recorded pulse wave at different vessels. Using the data to calculate the dynamic HRV(DHRV) and the pulse wave velocity(PWV). With the pulse wave velocity of different vessels and DHRV , we can understand the autonomic nerve activity and the local sympathetic nerve activity in different diseases and different sites. research 6 normal young people with no cardiovascular disease as control group. 5of them are male and 1 is female aged 23±2.The second group contains 10 people(7 males and 3 females), who have Diabetes mellitus(Type 2) without hypertension aged 54±11. The third group has only 2 males aged 50 and 37, are Diabetes mellitus(Type 2) patient with Charcot foot.hen the tilt-table tilts the change of PWV of lower limb is greater than upper limb. The change of PWV of lower limb in control group is greater than the other 2 groups. The DHRV of control is greater than the other 2 groups, and the DHRV of the patients with Charcot foot is much smaller. The change of MAP is positive in control, but negative in the other. Then we can prove that this technique can measure the activity of autonomic nervous sysyem.
Subjects
Autonomic neuropathy
Charcot foot
Pulse wave velocity
HRV
Diabetes
SDGs
Type
thesis
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