Gender disparities in optimal lipid control among patients with coronary artery disease
Journal
Journal of Atherosclerosis and Thrombosis
Journal Volume
21
Journal Issue
SUPPL. 1
Pages
S20-S28
Date Issued
2014
Author(s)
Chen C.-Y.
Chuang S.-Y.
Fang C.-C.
Huang L.-C.
Hsieh I.-C.
Pan W.-H.
Yeh H.-I.
Yin W.-H.
Chen J.-W.
Abstract
Coronary heart disease (CHD) is the leading cause of death worldwide in both men and women. Hypercholesterolemia is a major factor contributing to the incidence of CHD. Many lipid-lowering trials have shown statins to be effective medications for the primary and secondary prevention of CHD. Some studies have suggested that statins are as or more effective in women than in men. However, there is a substantial gender gap in lipid goal attainment with respect to primary care guidelines, as reported in observational studies. In this article, we attempt to explain gender differences in lipid control in individuals with or at risk of CHD in order to improve awareness of and narrow gaps in gender disparities in lipid management.
Subjects
Gender and cholesterol
Other Subjects
estrogen; high density lipoprotein cholesterol; hydroxymethylglutaryl coenzyme A reductase; lipid; low density lipoprotein cholesterol; low density lipoprotein receptor; pravastatin; simvastatin; article; awareness; cardiovascular mortality; cardiovascular risk; clinical practice; coronary artery disease; human; hypercholesterolemia; meta analysis (topic); morbidity; practice guideline; randomized controlled trial (topic); sex difference; Clinical Trials as Topic; Coronary Artery Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Sex Factors
Publisher
Japan Atherosclerosis Society
Type
journal article