Schisarisanlactones A and B: A new class of nortriterpenoids from the fruits of Schisandra arisanensis
Journal
Food Chemistry
Journal Volume
136
Journal Issue
2
Pages
1095-1099
Date Issued
2013
Author(s)
Abstract
Two novel highly oxygenated nortriterpenoids, schisarisanlactones A (1) and B (2), have been isolated from the fruits of Schisandra arisanensis, an endemic plant of Taiwan. Compounds 1 and 2 possess an unprecedented 5/5/7/5/5-fused pentacyclic ring system. The structures of both compounds were determined on the basis of spectroscopic analyses, especially 2D NMR and MS. A plausible biogenetic pathway of 1 was proposed. Schisarisanlactone A (1) showed significant anti-HIV activity. ? 2012 Elsevier Ltd. All rights reserved.
SDGs
Other Subjects
Anti-HIV activity; Biogenetic pathways; Endemic plants; Nortriterpenoids; Ring systems; Schisandra; Spectroscopic analysis; Fruits; anti human immunodeficiency virus agent; nortriterpenoid; plasmid vector; schisarisanlactone A; schisarisanlactone B; triterpenoid; unclassified drug; antiviral activity; article; biogenesis; carbon nuclear magnetic resonance; chemical structure; fruit; heteronuclear multiple bond correlation; heteronuclear multiple quantum coherence; Human immunodeficiency virus; in vitro study; isolation and purification; mass spectrometry; nonhuman; nuclear Overhauser effect; plant; proton nuclear magnetic resonance; real time polymerase chain reaction; Schisandra arisanensis; virus load; Anti-HIV Agents; Fruit; HIV; Molecular Structure; Plant Extracts; Schisandra; Taiwan; Triterpenes; Schisandra
Type
journal article