Biomedical engineering methods as potential treatment options for intervertebral disc degeneration
Journal
Biomedical Engineering - Applications, Basis and Communications
Journal Volume
17
Journal Issue
2
Pages
97-100
Date Issued
2005
Author(s)
Abstract
Degeneration of the intervertebral disc (IVD) and associated spinal disorders are a leading cause of morbidity resulting in substantial pain and increased health cost. Current treatment options may relieve some clinical symptoms but will never stop further degeneration in the IVD. In recent years, several investigations have been carried out trying to regenerate IVD tissue. These biomedical engineering methods aim to retard or even reverse the degenerative process and possibly regain a healthy IVD. In this review, recent progresses on each category of biomedical engineering approaches will be briefly introduced.
SDGs
Other Subjects
Health; Tissue; Health costs; Intervertebral disc (IVD); Morbidity; Spinal disorders; Biomedical engineering; agarose; basic fibroblast growth factor; biomaterial; bone morphogenetic protein; chondroitin; chondroitin 6 sulfate; collagen; collagen type 2; fibrin; gelatin; hyaluronic acid; LIM protein; somatomedin C; transcription factor Sox9; transforming growth factor beta; autotransplantation; biomedical engineering; cartilage cell; chondrogenesis; extracellular matrix; gene therapy; human; intervertebral disk; intervertebral disk degeneration; nonhuman; review
Publisher
Institute of Biomedical Engineering
Type
review