Synchronization between arterial blood pressure and cerebral oxyhaemoglobin concentration investigated by wavelet cross-correlation
Journal
Physiological Measurement
Journal Volume
28
Journal Issue
2
Pages
161-173
Date Issued
2007
Author(s)
Rowley A.B.
Payne S.J.
Tachtsidis I.
Ebden M.J.
Whiteley J.P.
Gavaghan D.J.
Tarassenko L.
Smith M.
Elwell C.E.
Delpy D.T.
Abstract
Wavelet cross-correlation (WCC) is used to analyse the relationship between low-frequency oscillations in near-infrared spectroscopy (NIRS) measured cerebral oxyhaemoglobin (O2Hb) and mean arterial blood pressure (MAP) in patients suffering from autonomic failure and age-matched controls. Statistically significant differences are found in the wavelet scale of maximum cross-correlation upon posture change in patients, but not in controls. We propose that WCC analysis of the relationship between O2Hb and MAP provides a useful method of investigating the dynamics of cerebral autoregulation using the spontaneous low-frequency oscillations that are typically observed in both variables without having to make the assumption of stationarity of the time series. It is suggested that for a short-duration clinical test previous transfer-function-based approaches to analyse this relationship may suffer due to the inherent nonstationarity of low-frequency oscillations that are observed in the resting brain. ? 2007 IOP Publishing Ltd.
Subjects
Blood pressure
Infrared devices
Time series analysis
Wavelet analysis
Arterial blood pressure
Cerebral circulation
Frequency oscillations
Lower frequencies
Mean arterial blood pressures
Posture change
Spontaneous oscillations
Sympathetic stimulation
Time-frequency Analysis
Wavelet cross-correlation
Near infrared spectroscopy
adult
aged
article
autonomic dysfunction
autoregulation
body posture
brain cortex
controlled study
correlation analysis
dynamics
hemoglobin determination
human
mean arterial pressure
near infrared spectroscopy
oscillation
priority journal
statistical significance
waveform
algorithm
autonomic neuropathy
blood pressure
brain level
female
homeostasis
male
metabolism
middle aged
pathophysiology
physiology
plethysmography
statistical analysis
supine position
tilt table test
oxyhemoglobin
Adult
Aged
Algorithms
Autonomic Nervous System Diseases
Blood Pressure
Brain Chemistry
Data Interpretation, Statistical
Female
Homeostasis
Humans
Male
Middle Aged
Oxyhemoglobins
Plethysmography
Spectroscopy, Near-Infrared
Supine Position
Tilt-Table Test
SDGs
Type
journal article