Ketamine abuse-induced uropathy and kidney injury
Journal
Journal of Internal Medicine of Taiwan
Journal Volume
26
Journal Issue
1
Pages
30-34
Date Issued
2015
Author(s)
Hsu W.-D.
Abstract
Ketamine has been applied for anesthetics both in veterinary and human medicine since 1960s. Because Ketamine can easily lead to dissociative illusion, it quickly becomes the commonly preference among young drug abusers in recent decades. Ketamine abusers frequently encounter bladder dysfunction, uropathy and kidney injury, which derived from the adverse effects of Ketamine with unknown mechanisms. The patients usually present lower urinary tract symptoms, including lower abdominal pain, urgency, dysuria, frequency and frank hematuria. Small bladder capacity, bladder wall thickening, hydronephrosis and renal tubulointerstitial injury are obviously detected by image, laboratory and pathological studies. Cessation of Ketamine abuse is the best way to prevent the progressive deterioration of renal function and treat the intractable urinary symptoms. Multi-disciplinary team approach is an important strategy to manage the Ketamirie abuse-induced uropathy.
SDGs
Other Subjects
ketamine; Article; bladder capacity; drug abuse; dysuria; hematuria; human; hydronephrosis; kidney injury; lower abdominal pain; lower urinary tract symptom; urinary tract disease
Publisher
Society of Internal Medicine of Taiwan
Type
journal article