Association between amebic liver abscess and human immunodeficiency virus infection in Taiwanese subjects
Journal
BMC Infectious Diseases
Journal Volume
8
Pages
48
Date Issued
2008
Author(s)
Abstract
Purpose: Invasive amebiasis is an emerging parasitic disorder in Taiwan, especially in patients diagnosed with human immunodeficiency virus (HIV) infection. Thirty-three Taiwanese subjects with amebic liver abscess (ALA) were examined and a possible correlation between ALA and HIV infection was investigated. Results: Among ALA patients, the proportion of HIV-positive individuals increased during the study period. ALA was the first major clinical presentation in 54% of HIV patients with ALA. Overall, 58% (14/24) of HIV-infected patients had a CD4+ count > 200 cells/μL and 82.1% (23/28) had no concurrent opportunistic infection or other evidence of HIV infection. There was no marked difference in clinical characteristics between HIV-positive and HIV-negative ALA patients except the level of leukocytosis. Conclusion: While the clinical characteristics described herein cannot be used to determine whether ALA patients have HIV infection, routine HIV testing is recommended in patients with ALA, even in the absence of HIV symptoms. ? 2008 Hsu et al; licensee BioMed Central Ltd.
SDGs
Other Subjects
idoquinol; idoquinolone; metronidazole; quinolone derivative; antiprotozoal agent; protozoon antibody; adult; aged; article; CD4 lymphocyte count; clinical article; clinical feature; concurrent infection; controlled study; correlation analysis; disease association; eradication therapy; female; human; Human immunodeficiency virus infected patient; Human immunodeficiency virus infection; laboratory test; leukocytosis; liver amebiasis; male; monotherapy; opportunistic infection; retrospective study; Taiwan; treatment duration; virus detection; blood; comorbidity; Human immunodeficiency virus infection; liver; liver amebiasis; middle aged; parasitology; pathology; Taiwan; Adult; Aged; Antibodies, Protozoan; Antiprotozoal Agents; CD4 Lymphocyte Count; Comorbidity; HIV Infections; Humans; Liver; Liver Abscess, Amebic; Male; Metronidazole; Middle Aged; Taiwan
Type
journal article