A recently-discovered NMDA receptor gene, GRIN3B, is associated with duration mismatch negativity
Journal
Psychiatry Research
Journal Volume
218
Journal Issue
3
Pages
356-358
Date Issued
2014
Abstract
The study explored associations between mismatch negativity and N-methyl- d-aspartic acid receptor subunit genes, GRIN1, GRIN2B and GRIN3B in healthy subjects and schizophrenia. Nineteen single-nucleotide polymorphisms were genotyped in 138 schizophrenia patients and 103 healthy subjects. Rs2240158 of GRIN3B was significantly associated with mismatch negativity in healthy subjects. ? 2014 Elsevier Ireland Ltd.
SDGs
Other Subjects
n methyl dextro aspartic acid receptor; neuroleptic agent; n methyl dextro aspartic acid receptor; nerve protein; adult; article; controlled study; disease duration; electroencephalography; female; gene; gene function; genetic analysis; genetic association; genetic heterogeneity; genotype; GRIN1 gene; GRIN2B gene; GRIN3B gene; haplotype; human; major clinical study; male; mismatch negativity; priority journal; schizophrenia; sequence analysis; single nucleotide polymorphism; case control study; genetic polymorphism; genetic predisposition; genetics; middle aged; reference value; schizophrenia; Adult; Case-Control Studies; Female; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Nerve Tissue Proteins; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Receptors, N-Methyl-D-Aspartate; Reference Values; Schizophrenia
Type
journal article