Eradication of intracellular Francisella tularensis in THP-1 human macrophages with a novel autophagy inducing agent
Journal
Journal of biomedical science
Journal Volume
16
Journal Issue
1
Date Issued
2009-12
Author(s)
Abstract
Autophagy has been shown recently to play an important role in the intracellular survival of several pathogenic bacteria. In this study, we investigated the effect of a novel small-molecule autophagy-inducing agent, AR-12, on the survival of Francisella tularensis, the causative bacterium of tularemia in humans and a potential bioterrorism agent, in macrophages.
SDGs
Type
journal article