A transition metal carbonyl probe for use in a highly specific and sensitive sers-based assay for glucose
Journal
Journal of the American Chemical Society
Journal Volume
135
Journal Issue
48
Pages
18028-18031
Date Issued
2013
Author(s)
Abstract
A triosmium carbonyl cluster-boronic acid conjugate is used as a secondary carbohydrate probe in a SERS-based assay. The assay does not require conjugation of the metal carbonyl probe to a SERS-active species, and it utilizes the CO stretching vibrations of the metal carbonyl, which lies in a silent region of the SERS spectrum (1800-2200 cm(-1)), for quantification. High selectivity for glucose over fructose and galactose is obtained, and a human urine sample doped with glucose is detected accurately.
Type
journal article