An Extremely Stable Host-Guest Complex That Functions as a Fluorescence Probe for Calcium Ions
Resource
Chemistry-A European Journal 12 (17): 4594-4599
Journal
Chemistry-A European Journal
Journal Volume
12
Journal Issue
17
Pages
4594-4599
Date Issued
2006
Date
2006
Author(s)
Abstract
Herein, we report a crown ether based molecular cage that forms extremely stable supramolecular complexes with dimethyldiazapyrenium (DMDAP) ions in CD(3)CN through the collaboration of multiple weak C-HO hydrogen bonds. The very strong binding affinity in this host-guest system allows the molecular cage to bleach the fluorescence signal of DMDAP substantially in equimolar solutions at concentrations as low as 1 x 10(-5) M. Remarkably, a 1x10(-5) M equimolar solution of the molecular cage and DMDAP is highly selective toward Ca(2+) ions-relative to other biologically important Li(+), Na(+), K(+), and Mg(2+) ions-and causes a substantial increase in the fluorescence intensity of the solution. As a result, this molecular cage/DMDAP complex behaves as a supramolecular fluorescence probe for the detection of Ca(2+) ions in solution.
Type
journal article
File(s)![Thumbnail Image]()
Loading...
Name
431.pdf
Size
188.38 KB
Format
Adobe PDF
Checksum
(MD5):8e17525162b79142c3d28c9500b7c4c3