行政院國家科學委員會補助專題研究計畫成果報告:鴨病毒性肝炎病毒之核酸定序與毒力因子分析
Date Issued
2002
Date
2002
Author(s)
DOI
902313B002312
Abstract
In this project, complete genoine sequence of non type 1 duck viral hepatitis virus (DFIV) was resolved for the first time. It was showed that the genome of the DHV composed of 8, 283 bp, and the virus should be belonged to a new genus in Plcornaviriclae. The virus had a 6, 978 bp long open reading frame which was translation into a polyprotein with 2, 325 aa. The 3¡¦ NTR (non-translation-region) of the polyprotein was 235 bp in size and the poly A tail a size if 67 bp. It was showed that the amino acid sequence of DHV was most similar to enterovirus and rhinovirus in the Ficornaviridae family, but only with 25.5% and 24.3% homology. Besides, DHV possessed a 268 aa L protein which was lacking in both enterovirus and rhinovirus. Pylogenetic analysis of the amino acid sequence of the 3D and the polyprotein region, it was showed by a boostrap value of 99% and 100% that DHV should be belonged to a new genus in Ficornavirudae.
Subjects
Duck Viral Hepatitis
Genome
Picornavirudae
SDGs
Publisher
臺北市：國立臺灣大學獸醫學系暨研究所
Type
report
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