Increased expression of mineralocorticoid receptor in human atrial fibrillation and a cellular model of atrial fibrillation
Journal
Journal of the American College of Cardiology
Journal Volume
55
Journal Issue
8
Pages
758
Date Issued
2010-02-23
Author(s)
Abstract
This study was designed to evaluate the status of steroidogenesis proteins and de novo synthesis of aldosterone in the atrium, and relationships of these factors to atrial fibrillation (AF).
Subjects
atrial fibrillation; aldosterone; mineralocorticoid receptor; ionic remodeling; spironolactone; ANGIOTENSIN-CONVERTING ENZYME; GENE-EXPRESSION; CALCIUM-CHANNEL; MESSENGER-RNA; ALDOSTERONE; KINASE; FIBROBLASTS; SUBSTRATE; PATHWAY
Publisher
ELSEVIER SCIENCE INC
Type
journal article