Heart rate and suicide: Findings from two cohorts of 533 000 Taiwanese and 75 000 Norwegian adults
Journal
Acta Psychiatrica Scandinavica
Journal Volume
133
Journal Issue
4
Pages
277-288
Date Issued
2016
Author(s)
Abstract
Objective: To investigate the association of resting heart rate with suicide in two large cohorts. Method: The MJ cohort (Taiwan) included 532 932 adults from a health check-up programme (1994-2008). The HUNT cohort (Norway) included 74 977 adults in the Nord-Tr?ndelag County study (1984-1986), followed up to 2004. In both cohorts heart rate was measured at baseline, and suicide was ascertained through linkage to cause-of-death registers. Risk of suicide was estimated using Cox proportional hazards models. Results: There were 569 and 188 suicides (average follow-up period of 8.1 and 16.9 years) in the MJ and HUNT cohorts respectively. Sex- and age-adjusted hazard ratio for every 10 beat increase in heart rate per minute was 1.08 (95% Confidence Interval 1.00-1.16) and 1.24 (1.12-1.38) in the MJ and HUNT cohorts, respectively. In the MJ cohort this association was confined to individuals with a history of heart diseases vs. those without such a history (P for interaction = 0.008). In the HUNT cohort the association did not differ by history of heart diseases and was robust to adjustment for health-related life style, medication use, and symptoms of anxiety and depression. Conclusion: Elevated resting heart rate may be a marker of increased suicide risk. ? 2016 John Wiley & Sons A/S.
Subjects
Cohort study; Heart rate; Norway; Suicide; Taiwan; The Hunt Study
SDGs
Other Subjects
adult; Article; controlled study; disease association; female; follow up; heart disease; human; major clinical study; male; medical history; middle aged; Norwegian (people); priority journal; resting heart rate; suicide; Taiwanese; cohort analysis; epidemiology; heart rate; Norway; physiology; proportional hazards model; risk factor; statistics and numerical data; suicide; Taiwan; young adult; Adult; Cohort Studies; Female; Heart Rate; Humans; Male; Middle Aged; Norway; Proportional Hazards Models; Risk Factors; Suicide; Taiwan; Young Adult
Type
journal article