Transition into Driven Equilibrium (TIDE) bSSFP MRI: Characteristics Analysis and Clinical Application
Date Issued
2014
Date
2014
Author(s)
Huang, Yin-Cheng Kris
Abstract
Transition into Driven Equilibrium (TIDE) balanced steady-state free precession
(bSSFP) sequence is a variant of bSSFP MRI technique that has been developed over
the last decade. The pulse sequence can be conceptually divided into two parts: a
TIDE preparation and a repetitive constant flip angle readout. The authors of this
thesis independently discovered fat suppression phenomenon during volunteer studies
of TIDE bSSFP, when transient-phase data were sampled and registered at central
k-space. In addition, this imaging method also shows a T2-weighted contrast. To
analyze these specific properties, we used simulations and mathematical deduction to
demonstrate concisely the evolution behaviors of on-resonance spins as well as
certain off-resonance spins. We recruited thirty healthy volunteers to validate the
image quality for TIDE bSSFP for use as an ultrafast multisection T2-weighted image
of the brain. For image quality comparison, turbo spin echo (TSE) and turbo gradient
spin-echo (TGSE) were also used. We also exhibited the differences between
imaging methods on a few patients with brain pathologies. As a result, TIDE bSSFP
provides T2-weighted images with reduced scan times and reduced motion artifact
interference compared with TSE and turbo gradient spin-echo, with the trade-off of
reduced SNR as well as poorer gray-white matter differentiation and iron load
sensitivity. In certain situations like patients with involuntary motions, TIDE bSSFP
technique may serve as a supplement to standard MRI methods.
Subjects
磁振造影
平衡穩定態自由旋進
漸變式驅動平衡
脂肪信號抑制
T2權重影像
Type
thesis
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