Effects of health intervention program on cardiometabolic risk profiles from health evaluation center in Asian population: A longitudinal study and propensity analysis
Journal
Health and Quality of Life Outcomes
Journal Volume
13
Journal Issue
1
Date Issued
2015
Author(s)
Abstract
Background: Health intervention program (HIP) based on diet and lifestyle modifications had been shown to improve cardiovascular risks. The effects of such program on a variety of cardiometabolic outcome measures conducted in a strict analysis remained relatively unexplored. Materials and methods: A total of 2,660 participants (mean age: 43.3 ± 10 years, 63.6 % male) underwent annual health survey from our health evaluation department. We implemented health intervention program (HIP) in which diet and lifestyle modifications including smoking cessation and advised physical activities were introduced. We further studied the effects of HIP on several cardiometabolic outcome measures including Framingham, metabolic scores and renal function in terms of Egfr with a mean follow-up period of 38.5 months. Propensity score (PS) matching (HIP vs non-HIP group) was used to avoid effects of case selection bias. Results: Totally 1,004 (502 subjects for each group) left after PS matching protocol (both HIP and non-HIP group). The HIP group showed significant decline of waist circumference (-1.46 ± 0.61, p = 0.016), post-prandial glucose (-6.77 ± 2.06, p = 0.001), and total cholesterol level (-4.42 ± 2.15, p = 0.04), with borderline increase in eGFR (1.72 ± 0.94, p = 0.068) after an average of 1.91 ± 1.14 year follow up period. Exercise behavior significantly increased for those who received HIP when compared to the non-HIP group (44.6 vs 52.4 %, p = 0.014). PS matching and difference-in-difference (DID) analysis further confirmed the beneficial effects of ATP III reduction by HIP (-0.36 ± 0.06, p < 0.05). Conclusion: We demonstrated in our study that several cardiometabolic profiles can be substantially improved after health intervention introduction at the health evaluation center, supporting the beneficial evidence of such health intervention programs implementation based on primary prevention view points. ? 2015 Liu et al.
Subjects
Cardiometabolic profiles; Health promotion; Primary prevention; Propensity matching
SDGs
Other Subjects
cholesterol; glucose; hemoglobin A1c; high density lipoprotein; low density lipoprotein; adult; Article; Asian; body mass; cardiometabolic risk; cholesterol blood level; diet restriction; exercise; female; glucose blood level; health program; health promotion; human; human cell; intervention study; lifestyle modification; lipoprotein blood level; longitudinal study; male; mass screening; physical activity; population research; smoking cessation; waist circumference; aged; Asian continental ancestry group; Cardiovascular Diseases; counseling; diet; lifestyle; middle aged; procedures; quality of life; risk; statistics and numerical data; Aged; Asian Continental Ancestry Group; Cardiovascular Diseases; Counseling; Diet; Exercise; Female; Health Promotion; Humans; Life Style; Longitudinal Studies; Male; Middle Aged; Quality of Life; Risk
Type
journal article