Programmable one-pot synthesis of tumor-associated carbohydrate antigens Lewis X dimer and KH-1 epitopes
Resource
TETRAHEDRON LETTERS, 52(17), 2132-2135
Journal
Tetrahedron Letters
Pages
2132-2135
Date Issued
2011
Date
2011
Author(s)
Tsai, Bin-Ling
Han, Jeng-Liang
Ren, Chien-Tai
Wu, Chung-Yi
Wong, Chi-Huey
Abstract
The total synthesis of the antigenic Lewis X (Lex) dimer and KH-1 epitopes by a reactivity-based programmable one-pot synthetic strategy is reported. This approach can minimize the protection-deprotection and purification steps. Using the reactivity-based one-pot synthetic method, the fully protected Lewis X (Lex) dimer and KH-1 epitopes were furnished in a facile manner, which were globally deprotected to give the Lex dimer and KH-1 epitopes. © 2010 Elsevier Ltd. All rights reserved.
Type
journal article
File(s)![Thumbnail Image]()
Loading...
Name
145.pdf
Size
23.23 KB
Format
Adobe PDF
Checksum
(MD5):c4313b67be581320db2c54a31061e2bd