Glycolipids from the Formosan Soft Coral Lobophytum crassum
Resource
CHEMICAL & PHARMACEUTICAL BULLETIN 55 (12): 1720
Journal
Chemical and Pharmaceutical Bulletin
Journal Volume
55
Journal Issue
12
Pages
1720-1723
Date Issued
2007
Date
2007
Author(s)
Abstract
Three glycolipids (1-3), possessing a sugar moiety at C-2 of glycerol ether, have been isolated from the Formosan soft coral Lobophytum crassum. Their structures were elucidated by spectroscopic methods, particularly in 1D- and 2D-NMR experiments. The absolute configurations on the sugar portion and lipid aglycon of 1-3 were determined by methanolysis, chemical transformation and the application of Mosher's method on 1 and 3. Compounds 1-3 exhibited weak cytotoxic activities. ? 2007 Pharmaceutical Society of Japan.
Subjects
Arabinopyranoside; Coral; Glycolipid; Lobophytum crassum; R-batyl alcohol; R-chimyl alcohol
Other Subjects
1 acetoxy 3 hexadecyloxypropyl beta dextro arabinopyranoside; 1 hydroxy 3 hexadecyloxypropyl beta dextro arabinopyranoside; 1 hydroxy 3 octadecyloxypropyl beta dextro arabinopyranoside; glycolipid; unclassified drug; article; cancer cell; controlled study; coral; cytotoxicity; drug isolation; drug structure; drug transformation; human; human cell; Lobophytum crassum; methanolysis; nuclear magnetic resonance spectroscopy; proton nuclear magnetic resonance; Animals; Anthozoa; Antineoplastic Agents; Cell Line, Tumor; Chromatography, Thin Layer; Drug Screening Assays, Antitumor; Glycolipids; Humans; Hydrolysis; Indicators and Reagents; Mass Spectrometry; Taiwan
Type
journal article
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