Associations between particulate sulfate and organic carbon exposures and heart rate variability in patients with or at risk for cardiovascular diseases
Journal
Journal of Occupational and Environmental Medicine
Journal Volume
49
Journal Issue
6
Pages
610-617
Date Issued
2007
Author(s)
Abstract
OBJECTIVE: It is still unknown whether specific components in fine particles are associated with heart rate variability (HRV) reduction. METHODS: We recruited 46 patients with or at risk for cardiovascular diseases to measure 24-hour HRV by ambulatory electrocardiographic monitoring. Fixed-site air-monitoring stations were used to represent participants' exposures to particles with aerodynamic diameters less than 10 μm (PM10) and 2.5 μm (PM2.5), and particulate components of sulfate, nitrate, organic carbon (OC) and elemental carbon, and gaseous pollutants. RESULTS: We found that HRV reduction was associated with sulfate, OC, and PM2.5 but not with the other five pollutants in single-pollutant models. Sulfate was found to remain in significant association with HRV reduction adjusting for OC and PM2.5 in three-pollutant models. CONCLUSIONS: Exposures to sulfate and OC in PM2.5 were associated with HRV reduction in patients with or at risk for cardiovascular diseases. ?2007The American College of Occupational and Environmental Medicine.
Other Subjects
nitrate; organic carbon; sulfate; adult; aged; air monitoring; article; cardiovascular disease; cardiovascular risk; clinical article; electrocardiography; environmental exposure; female; heart rate variability; human; male; monitoring; particle size; pollutant; risk assessment; Adult; Aged; Aged, 80 and over; Carbon; Cardiovascular Diseases; Electrocardiography; Female; Health Status; Heart Rate; Humans; Male; Middle Aged; Monitoring, Physiologic; Particulate Matter; Risk; Sulfates; Taiwan
Type
journal article