Fiber-optics Based Optical Coherence Tomography for Biomedical Application
Other Title
生醫應用之光纖式光學同調斷層掃描
Journal
Journal of Medical and Biological Engineering
Journal Volume
23
Journal Issue
1
Start Page
7
End Page
12
Date Issued
2003
Author(s)
Abstract
Optical coherence tomography (OCT) is a fast evolving noninvasive imaging technology for biomedicine in recent years. Its fundamental principle is to use a low coherent light on biological sample and collect the backscattering light with an interferemeter configuration. It can achieve high spatial resolution of several micrometers and reconstruct two or three-dimensional images with various scanning mechanisms. Based on a fiber-optics based OCT, we implemented an optical delay-line on the reference arm for fast scanning speed and a handheld probe on sampling arm for surface scanning applications. We also reported a simple image compensation scheme, which is based on the distortion profile of scan depth, to enhance the image quality.
光學同調斷層掃描,為近年來快速進步的非侵入式醫學造影系統,其基本原理為使用低同調之光源,照射於生物組織,並以反射式干涉術量測背向散射光,可藉由不同機制之掃描方式,重建出二維或三維之生物組織影像,並具有達微米級之高空間解析度。我們完成一套光纖式光學同調斷層掃描系統,為了增加系統之臨床實用性,故以光學相位延遲器做為參考端之快速掃描,配合手持式造影探頭為樣本端之掃描,亦針對掃描深度之強度失真問題,進行最佳化補償,以增進影像之品質。
Subjects
Optical coherence tomography
Optical phase delay line
Handheld probe
Imaging distortion compensation
光學同調斷層掃描
光學相位延遲器
手持式造影探頭
影像失真補償
Type
journal article
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