Does physical activity protect older persons with frailty and cognitive impairment from excess all-cause mortality?
Journal
Archives of Gerontology and Geriatrics
Journal Volume
97
Date Issued
2021
Author(s)
Abstract
Objectives: The main aim of this study was to examine how physical activity in combination with physical frailty and cognitive impairment affects risk of mortality in older adults. Study Design: A national sample of community-dwelling Taiwanese aged 65 years or older (n=2678) was followed for 5 years. Main outcome measures: Frailty was determined based on the Fatigue, Resistance, Ambulation, Illness, and Loss of weight (FRAIL) scale. The Mini-Mental State Examination was used to assess cognitive impairment. Information on self-reported physical activity was collected at baseline. The study cohort was followed until the date of death or the end of the study period (31 December 2018). Deaths were confirmed by the computerized data files of the National Register of Deaths. Results: A total of 417 deaths were recorded after 12415.2 person-years of follow-up. After adjustment for other factors, compared with active participants who were physically robust with normal cognition, inactive participants who were with either frail/pre-frail or cognitively impaired had hazard ratios for mortality of 2.65 (95% CI=[1.88-3.74]) and 3.09 (95% CI=[2.08-4.59]), respectively. Inactive participants with coexisting frailty/pre-frailty and cognitive impairment had the highest hazard ratio for mortality of 3.85 (95% CI=[2.73-5.45]). Being active was associated with a mortality reduction of 31%, 38%, and 42% in physically robust participants with normal cognition, those who were frail/pre-frail only, and those with cognitive impairment only, respectively. Conclusions: Having a physically active life style has beneficial effects on survival in older persons with either frailty/pre-frailty or cognitive impairment. ? 2021 Elsevier B.V.
Subjects
Cognitive impairment
Frailty
Mortality
Physical activity
Taiwan
aged
cognitive defect
exercise
frail elderly
frailty
geriatric assessment
human
very elderly
Aged
Aged, 80 and over
Cognitive Dysfunction
Exercise
Frail Elderly
Geriatric Assessment
Humans
SDGs
Type
journal article