Taiwan ocular inflammation society consensus recommendations for the management of juvenile idiopathic arthritis-associated uveitis
Journal
Journal of the Formosan Medical Association = Taiwan yi zhi
Date Issued
2024-02-28
Author(s)
Chen, Wei-Dar
Wu, Cheng-Hsiu
Wu, Po-Yi
Ou, Liang-Shiou
Hwang, De-Kuang
Sheu, Shwu-Jiuan
Chiang, Wei-Yu
Chang, Yo-Chen
Lin, Chun-Ju
Chan, Wei-Chun
Fang, Yueh-Fu
Chien-Chieh Huang, Jerry
Kao, Tzu-En
Chiu, Fang-Yi
Hsia, Ning-Yi
Hwang, Yih-Shiou
Abstract
We presented the development of a consensus guideline for managing juvenile idiopathic arthritis-associated uveitis (JIAU) in Taiwan, considering regional differences in manifestation and epidemiology. The Taiwan Ocular Inflammation Society (TOIS) committee formulated this guideline using a modified Delphi approach with two panel meetings. Recommendations were based on a comprehensive evidence-based literature review and expert clinical experiences, and were graded according to the Oxford Centre for Evidence-Based Medicine's "Levels of Evidence" guideline (March 2009). The TOIS consensus guideline consists of 10 recommendations in four categories: screening and diagnosis, treatment, complications, and monitoring, covering a total of 27 items. These recommendations received over 75% agreement from the panelists. Early diagnosis and a coordinated referral system between ophthalmologists and pediatric rheumatologists are crucial to prevent irreversible visual impairment in children with JIAU. However, achieving a balance between disease activity and medication use remains a key challenge in JIAU management, necessitating further clinical studies.
Subjects
Anti-tumor necrosis factor; DMARDs; Juvenile idiopathic arthritis-associated uveitis; Methotrexate; Taiwan
SDGs
Type
journal article