Updated comprehensive epidemiology, microbiology, and outcomes among patients with acute cholangitis
Journal
Journal of Hepato-Biliary-Pancreatic Sciences
Journal Volume
24
Journal Issue
6
Pages
310-318
Date Issued
2017
Author(s)
Gomi H.
Takada T.
Hwang T.-L.
Akazawa K.
Mori R.
Endo I.
Miura F.
Kiriyama S.
Matsunaga N.
Itoi T.
Yokoe M.
Chen M.-F.
Jan Y.-Y.
Ker C.-G.
Wada K.
Yamaue H.
Miyazaki M.
Yamamoto M.
Abstract
Background: The international practice guidelines for patients with acute cholangitis and cholecystitis were released in 2007 (TG07) and revised in 2013 (TG13). This study investigated updated epidemiology and outcomes among patients with acute cholangitis on a larger scale for the first time. Methods: This is an international multi-center retrospective observational study in Japan and Taiwan. All consecutive patients older than 18?years of age and given a clinical diagnosis of acute cholangitis by clinicians between 1 January 2011 and 31 December 2012 were enrolled. Those who met the diagnostic criteria of acute cholangitis by TG13 were statistically analyzed. Results: A total of 7,294 patients were enrolled and 6,433 patients met the TG13 diagnostic criteria. The severity distribution was Grade I (37.5%), Grade II (36.2%), and Grade III (26.2%). The 30-day all-cause mortality was 2.4%, 4.7%, and 8.4% in Grade I, II, III severity, respectively (P?
Subjects
Acute cholangitis; Epidemiology; Microbiology; Mortality
SDGs
Other Subjects
adult; aged; Article; cholangitis; clinical outcome; controlled study; disease severity; endocarditis; female; human; incidence; Japan; liver abscess; major clinical study; male; microbiological examination; mortality; multicenter study; nonhuman; observational study; retrospective study; Taiwan; acute disease; age distribution; cholangitis; clinical trial; cohort analysis; immunohistochemistry; international cooperation; microbiology; middle aged; needle biopsy; prognosis; severity of illness index; sex ratio; survival rate; very elderly; antiinfective agent; Acute Disease; Age Distribution; Aged; Aged, 80 and over; Anti-Bacterial Agents; Biopsy, Needle; Cholangitis; Cohort Studies; Female; Humans; Immunohistochemistry; Incidence; Internationality; Japan; Male; Middle Aged; Prognosis; Retrospective Studies; Severity of Illness Index; Sex Distribution; Survival Rate; Taiwan
Publisher
Blackwell Publishing Asia
Type
journal article