Study on Yang-Xu Using Body Constitution Questionnaire and Blood Variables in Healthy Volunteers
Journal
Evidence-based Complementary and Alternative Medicine
Journal Volume
2016
Date Issued
2016
Author(s)
Abstract
Traditional Chinese medicine (TCM) formulates treatment according to body constitution (BC) differentiation. Different constitutions have specific metabolic characteristics and different susceptibility to certain diseases. This study aimed to assess the Yang-Xu constitution using a body constitution questionnaire (BCQ) and clinical blood variables. A BCQ was employed to assess the clinical manifestation of Yang-Xu. The logistic regression model was conducted to explore the relationship between BC scores and biomarkers. Leave-one-out cross-validation (LOOCV) and K-fold cross-validation were performed to evaluate the accuracy of a predictive model in practice. Decision trees (DTs) were conducted to determine the possible relationships between blood biomarkers and BC scores. According to the BCQ analysis, 49% participants without any BC were classified as healthy subjects. Among them, 130 samples were selected for further analysis and divided into two groups. One group comprised healthy subjects without any BC (68%), while subjects of the other group, named as the sub-healthy group, had three BCs (32%). Six biomarkers, CRE, TSH, HB, MONO, RBC, and LH, were found to have the greatest impact on BCQ outcomes in Yang-Xu subjects. This study indicated significant biochemical differences in Yang-Xu subjects, which may provide a connection between blood variables and the Yang-Xu BC. ? 2016 Hong-Jhang Chen et al.
SDGs
Other Subjects
alanine aminotransferase; albumin; aspartate aminotransferase; C reactive protein; creatinine; hemoglobin; high density lipoprotein cholesterol; hydrocortisone; low density lipoprotein cholesterol; luteinizing hormone; prasterone; thyrotropin; adult; Article; assessment of humans; body constitution; body constitution questionnaire; decision tree; erythrocyte count; female; hematocrit; human; human experiment; leave one out cross validation; leukocyte count; logistic regression analysis; male; mean corpuscular volume; normal human; questionnaire; urea nitrogen blood level; yang deficiency
Type
journal article
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