Progression of Pre-Hypertension, Stage 1 and 2 Hypertension (Jnc 7): A Population-Based Study in Keelung, Taiwan (Keelung Community-Based Integrated Screening No. 9)
Resource
JOURNAL OF HYPERTENSION v.24 n.5 pp.821-828
Journal
JOURNAL OF HYPERTENSION
Journal Volume
v.24
Journal Issue
n.5
Pages
821-828
Date Issued
2006
Date
2006
Author(s)
CHIU, YUEH-HSIA
WU, SHIAO-CHI
TSENG, CHUEN-DEN
YEN, AMY MING-FANG
CHEN, TONY HSIU-HSI
Abstract
Objective: To investigate the prevalence and progression of, and identify risk factors for, pre-hypertension, stage 1 and 2 hypertension in a population-based study. Design: A prospective cohort study. Setting: An integrated community- based multiple screening program in Keelung, Taiwan. Participants: A total of 67 011 individuals aged 20-79 years between 1999 and 2003 were included. Of these, 22 111 reattended, yielding 53 689 repeated recordings of blood pressure, including movement between normal and prehypertension and progression from pre-hypertension to stage 1 or stage 2 hypertension. Main outcome measures: Blood pressure was defined and classified according to the JNC 7 Report as normal, prehypertension, stage 1, and stage 2 hypertension. Results: Below 50 years of age, males had a higher progression rate, particularly from normal to prehypertension , than females. Annual regression rates from pre-hypertension to normal were higher in the young age group than in the old age group, particularly for females. Factors associated with the occurrence of pre-hypertension were old age, male gender, high waist circumference, abnormal blood lipids , smoking, chewing betel nuts, lack of exercise, and having parents with hypertension. Factors associated with regression from pre-hypertension to normal were body mass index, fasting glucose, high-density lipoprotein level, smoking, and parents with hypertension. Progression from pre- hypertension to stage 1 hypertension was positively related to male gender , higher waist circumference, and having parents with hypertension. Conclusions: The rates of progression and regression of hypertension vary with age and gender, anthropometric and biochemical measurements, and family history. J Hypertens 24 :821 - 828 (c) 2006 Lippincott Williams & Wilkins.
Subjects
hypertension
JNC 7 Report
multi-state transition
pre- hypertension
Type
journal article