Penicillamine induced lupus-like syndrome: A case report
Journal
Journal of Microbiology, Immunology and Infection
Journal Volume
33
Journal Issue
3
Pages
202-204
Date Issued
2000
Author(s)
Abstract
Several drugs have been suggested to cause lupus-like syndrome. However, penicillamine-induced lupus-like syndrome has only rarely been reported in patients with Wilson's disease. We describe a 6- year-old Taiwanese girl, with a diagnosis of Wilson's disease in November, 1997, who developed lupus-like syndrome 17 months after penicillamine treatment. After treatment with prednisolone and decrease in the dose of penicillamine, her symptoms subsided gradually. This is the first such case reported in a Taiwanese patient. Because the symptoms of drug-induced lupus (DIL) are nonspecific, subjective and variable, the diagnosis of DIL requires awareness of DIL-inducing potential of chronic medication.
SDGs
Other Subjects
acebutolol; captopril; carbamazepine; chlorpromazine; hydralazine; isoniazid; methyldopa; minocycline; penicillamine; prednisolone; procainamide; propylthiouracil; quinidine; salazosulfapyridine; article; case report; female; human; human tissue; long term care; preschool child; symptomatology; systemic lupus erythematosus; Taiwan; Wilson disease; Case Report; Child; Female; Human; Lupus Erythematosus, Systemic; Penicillamine
Type
journal article