Immunohistochemical localization of deoxyribonuclease I in rat parotid gland
Journal
Journal of the Otolaryngological Society of the Republic of China
Journal Volume
32
Journal Issue
6
Pages
620-626
Date Issued
1997
Author(s)
Abstract
Background: Deoxyribonuclease (DNase) is one of the digestive enzymes secreted by the parotid gland. Recent progresses in molecular biology and biochemistry have enabled us to learn more about the function of DNase in cells. In addition to its well-known digestive function, DNase was found to be closely related to some cancers and apoptosis. Methods: We use immunohistochemical techniques with purified antibody to study the distribution of DNase I in rat pancreas and parotid gland. Results: Rat DNase I is localized in secretary ganules of parotid gland but not found in pancreaS. Conclusions: Our results suggest that the role in digestive function of parotid gland may differ among different species and localization of DNase I may help us to the further study of parotid gland in cell biology.
Subjects
Deoxyribonuclease I; Immunohistochemistry; Parotid gland
SDGs
Other Subjects
deoxyribonuclease i; animal tissue; apoptosis; article; enzyme localization; enzyme release; nonhuman; pancreas; parotid gland; rat; secretory granule
Type
journal article