Systemic steroids in acute exacerbation of COPD - From guidelines to bedside
Journal
International Journal of Clinical Pharmacology and Therapeutics
Journal Volume
49
Journal Issue
11
Pages
705-708
Date Issued
2011
Author(s)
Abstract
The optimal steroid dosages in AECOPD are still under debate. Admission records of patients in our hospital from January to December 2008 due to a diagnosis of AECOPD were reviewed. More wheezing and tachypnea were noted in the patients with a maximal daily prednisolone dose more than 60 mg. The steroid dose was higher in AECOPD without pneumonia than those concurrent with pneumonia. Those who had concurrent pneumonia had a higher risk of nosocomial infections. The study reflects the heterogeneity of AECOPD and that steroid dosages were determined by the clinical evaluation of the severity of illness and bacterial infections. ?2011 Dustri-Verlag Dr. K. Feistle.
SDGs
Other Subjects
antibiotic agent; corticosteroid; prednisolone; steroid; article; bacterial infection; chronic obstructive lung disease; clinical evaluation; comorbidity; controlled study; disease exacerbation; disease severity; hospital infection; human; infection risk; major clinical study; outcome assessment; pneumonia; point of care testing; practice guideline; risk assessment; systemic therapy; treatment duration; unspecified side effect; Acute Disease; Adrenal Cortex Hormones; Humans; Practice Guidelines as Topic; Pulmonary Disease, Chronic Obstructive; Retrospective Studies
Type
journal article