Management Consensus Guidelines for Hepatocellular Carcinoma: 2023 Update on Surveillance, Diagnosis, Systemic Treatment, and Posttreatment Monitoring by the Taiwan Liver Cancer Association and the Gastroenterological Society of Taiwan.
Journal
Liver cancer
Journal Volume
13
Journal Issue
5
Pages
468 - 486
ISSN
2235-1795
Date Issued
2024-10
Author(s)
Teng, Wei
Wang, Hung-Wei
Lin, Shi-Ming
Chen, Kuan-Yang
Hu, Jui-Ting
Wang, Shen-Yung
Lin, Chih-Lin
Chang, Ching-Wei
Chau, Gar-Yang
Chen, San-Chi
Chen, Chia-Hsien
Cheng, Pin-Nan
Dai, Chia-Yen
Hsieh, Chia-Hsun
Huang, Yi-Hsiang
et al.,
Abstract
Hepatocellular carcinoma (HCC) is the leading cause of cancer-related mortality in Taiwan. The Taiwan Liver Cancer Association and the Gastroenterological Society of Taiwan established HCC management consensus guidelines in 2016 and updated them in 2023. Current recommendations focus on addressing critical issues in HCC management, including surveillance, diagnosis, systemic treatment, and posttreatment monitoring. For surveillance and diagnosis, we updated the guidelines to include the role of protein induced by vitamin K absence or antagonist II (PIVKA-II) and gadoxetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) in detecting HCCs. For systemic treatment, the updated guidelines summarize the multiple choices available for targeted therapy, immune checkpoint inhibitors, and a combination of both, especially for those carcinomas refractory to or unsuitable for transarterial chemoembolization. We have added a new section, posttreatment monitoring, that describes the important roles of PIVKA-II and EOB-MRI after HCC therapy, including surgery, locoregional therapy, and systemic treatment. Through this update of the management consensus guidelines, patients with HCC may benefit from optimal diagnosis, therapeutic modalities, and posttreatment monitoring.
Subjects
Diagnosis
Guideline
Hepatocellular carcinoma
Posttreatment monitoring
Surveillance
Systemic treatment
SDGs
Publisher
S. Karger AG
Type
journal article