Effects of diabetes on female voiding behavior
Journal
Journal of Urology
Journal Volume
172
Journal Issue
3
Pages
989-992
Date Issued
2004
Author(s)
Abstract
Purpose: We studied voiding behavior in women with type 2 diabetes vs nondiabetic female controls and examined factors associated with voiding dysfunction in patients with diabetes. Materials and Methods: After eliminating coexisting medical factors that could affect voiding function we evaluated voiding behaviors in 194 female patients with diabetes treated regularly at a diabetic clinic and 162 control women using a lower urinary tract symptom questionnaire based mainly on the American Urological Association Symptom Index questionnaire and free flow analyses with post-void residual urine estimates. Emptying efficiency was defined as 100% x volume voided/(volume voided + post-void residual urine). Results: Compared with controls patients with diabetes had significantly higher nocturia scores (p = 0.003), weaker urinary streams (p = 0.02), less voided volumes (220 ± 97 vs 280 ± 104 ml, p = 0.04) and lower maximal flow rates (19.4 ± 8.4 vs 25.9 ± 8.5 ml per second, p <0.001). Remarkable residual urine (100 ml or greater) was detected in 1.8% of controls vs 13.9% of patients. After controlling for age and voided volume diabetes was significantly associated with a decrease in baseline maximum flow of 4.5 ml per second (95% CI 2.9 to 6.2). In patients with diabetes peripheral neuropathy was an independent factor associated with the decrease in emptying efficiency (p = 0.03). Conclusions: Diabetes significantly altered voiding patterns in a significant proportion of women treated at the diabetic clinic. Peripheral neuropathy is an important factor associated with diabetic voiding dysfunction.
SDGs
Other Subjects
adult; age; aged; article; bladder emptying; controlled study; diabetic neuropathy; disease association; female; human; major clinical study; medical society; micturition; micturition disorder; non insulin dependent diabetes mellitus; outpatient department; peripheral neuropathy; priority journal; questionnaire; symptom; urethra
Publisher
Lippincott Williams and Wilkins
Type
journal article