Anti-inflammatory and hepatoprotective activity of Peh-Hue-Juwa-Chi-Cao in male rats
Journal
American Journal of Chinese Medicine
Journal Volume
30
Journal Volume
30
Journal Issue
2-3
Journal Issue
2-3
Pages
225-234
Start Page
225
End Page
234
ISSN
0192415X
Date Issued
2002
Author(s)
Abstract
Peh-Hue-Juwa-Chi-Cao (PHJCC) is a common commercial name for the herbal extract of either Hedyotis diffusa (HD), H. corymbosa (HC), or Mollugo pentaphylla (MP). The present study was carried out to investigate the anti-inflammatory and hepatoprotective effects of these three extracts in rats. The results indicated that extracts of HC, HD and MP possess anti-inflammatory activity, and that MP has the greatest inhibition against carrageenan-induced paw edema. In the hepatoprotective study, results indicated that the three plant extracts significantly reduced the acute elevation of serum glutamate oxalate transaminase (sGOT) and serum glutamate pyruvate transaminase (sGPT) concentration, and alleviated the degree of liver damage 24 hours after the intraperitoneal administration of hepatotoxins.
Subjects
Anti-Inflammatory Activity
H. corymbosa
Hedyotis diffusa
Hepatoprotective Effect
Mollugo pentaphylla
Type
journal article