Epidemiology, treatment pattern and health care utilization of myopic choroidal neovascularization: a population based study.
Journal
Japanese journal of ophthalmology
Journal Volume
61
Journal Issue
2
Pages
159-168
Date Issued
2017-03
Author(s)
Abstract
Purpose: To investigate the prevalence and incidence of myopic choroidal neovascularization (CNV) in Taiwan, including the health care utilization and treatment-associated costs. Methods: A retrospective cohort study using existing data from the Taiwanese National Health Insurance claims database to identify patients who had a diagnosis of myopic CNV recorded from 1 January 2009 to 31 December 2011. The prevalence of myopic CNV was monitored during this period, and the frequency and cost of both treatment visits and monitoring visits were analyzed for 2?years following diagnosis. Results: The prevalence of myopic CNV was 0.017%. In total, 9068 patients with myopic CNV were identified, 12.3% (n?=?1111) of whom were treated. Of those treated, 72.0% (n?=?800) received intravitreal anti-vascular endothelial growth factor injections (IVI); the remainder received either photodynamic therapy with verteporfin (vPDT), laser photocoagulation, or a combination of therapies. IVI was associated with the largest number of treatment visits as well as a higher administrative (non-drug) cost per treatment visit (a mean of USD?57.18). vPDT alone was associated with a higher overall cost per treatment visit and more monitoring visits than IVI or laser photocoagulation. Costs for monitoring visits were highest for IVI. Conclusions: The prevalence of myopic CNV was lower than that reported in previous studies, possibly because of differences in age distribution in the populations studied. The frequencies of treatment administered were similar to those reported in previous studies; however, a cost-effectiveness comparison could not be made owing to lack of data in previous studies. ? 2017, Japanese Ophthalmological Society.
Subjects
Epidemiology; Myopia; Neovascularization; Ranibizumab; Taiwan
SDGs
Other Subjects
vascular endothelial growth inhibitor; verteporfin; adult; Article; cohort analysis; female; health care cost; health care utilization; human; laser coagulation; major clinical study; male; myopia; national health insurance; patient monitoring; photodynamic therapy; population research; prevalence; priority journal; subretinal neovascularization; Choroidal Neovascularization; complication; eye fundus; fluorescence angiography; follow up; health survey; incidence; middle aged; Myopia, Degenerative; patient attitude; procedures; retrospective study; Taiwan; Choroidal Neovascularization; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Incidence; Male; Middle Aged; Myopia, Degenerative; Patient Acceptance of Health Care; Population Surveillance; Retrospective Studies; Taiwan
Type
journal article