18 Years Surgical Experience With Mediastinal Mature Teratoma
Journal
Journal of the Formosan Medical Association
Journal Volume
109
Journal Issue
4
Pages
287-292
Date Issued
2010
Author(s)
Abstract
Background/Purpose: Few studies have examined the surgical outcomes of mediastinal mature teratoma in Taiwan. In the present study, the clinicopathological characteristics of mature teratoma and their impact on surgical outcome were analyzed. Methods: From 1988 to 2005, 57 cases of mediastinal mature teratoma were reviewed. We collected and analyzed data about patient age, sex, symptoms, blood sugar, pulmonary function, diagnosis, tumor size, histopathological features, operative methods, operative time, tumor adhesion, blood loss, ventilator requirement, intensive care unit stay, chest tube requirement, and postoperative hospital stay. Results: There were 18 male and 39 female patients with a median age of 27 years. Forty-three patients received conventional open surgery, whereas 14 received video-assisted thoracoscopic surgery. The patients in the thoracoscopic group had a decreased operative time (106.4 ± 35.7 min vs. 205.4 ± 75.7 min, p = 0.038), fewer ventilator days (0.2 ± 0.4 vs. 0.5 ± 0.8, p = 0.034), and a shorter stay in the intensive care unit (0.6 ± 0.8 days vs. 1.5 ± 1.4 days, p = 0.030). Pancreatic tissue was identified in 21 of 57 tumors (36.8%). The patients with tumors that contained pancreatic tissue had more presenting symptoms and complicated surgery than those whose tumors were without pancreatic tissue (76.2% vs. 33.3%, p = 0.002, and 42.9% vs. 11.1%, p = 0.008). The patients with symptoms had a higher incidence of complicated surgery than those without (39.3% vs. 6.9%, p = 0.004). Conclusion: Mediastinal mature teratoma commonly occurs in young women. Thoracoscopic surgery is a feasible technique for mediastinal mature teratoma resection if no dense adhesions are found during preoperative assessment. The presence of symptoms might be a relative contraindication for thoracoscopic teratoma resection because of its association with surgical complications. ? 2010 Formosan Medical Association & Elsevier.
SDGs
Other Subjects
adolescent; adult; aged; article; bleeding; cancer surgery; chest tightness; child; coughing; endoscopic surgery; experience; female; fever; histopathology; human; human tissue; intensive care unit; length of stay; major clinical study; male; malignant teratoma; mediastinum; medical record review; operation duration; retrospective study; school child; surgical technique; thorax pain; treatment outcome; tube; tumor volume; Adolescent; Adult; Aged; Child; Female; Humans; Intensive Care Units; Length of Stay; Male; Mediastinal Neoplasms; Middle Aged; Postoperative Complications; Retrospective Studies; Sex Distribution; Taiwan; Teratoma; Thoracic Surgery, Video-Assisted; Thoracoscopy; Treatment Outcome; Young Adult
Type
journal article