Distribution of thalamic nociceptive neurons activated from the tail of the rat
Resource
Brain Research 498 (1): 118-122
Journal
Brain Research
Journal Volume
498
Journal Issue
1
Pages
118-122
Date Issued
1989
Date
1989
Author(s)
Abstract
The purpose of the present study was to map systematically in the thalamus the distribution of neurons processing nociceptive information from the tail of the rat. Pentobarbital-anesthetized and gallamine-paralyzed rats were used. Glass microelectrodes were used to record extracellularly from thalamic neurons. Noxious radiant heat stimuli were applied to the tail with a tail-flick apparatus, and the recorded neurons were localized with horseradish peroxidase deposits or by making electrodes left in situ. A number of 121 neurons were tested of which 45 responded. Of these, 13 were located in the ventrobasal complex (VB), 17 were located in the central lateral nucleus and the parafascicular nucleus of the intralaminar nuclei (ILN). The rest of the responding neurons were located in the posterior group, the reticular thalamic nucleus, and the zona incerta. The nucleus submedius was not examined specifically. It is concluded that the VB and the ILN are two of the most important thalamic nuclei for processing nociceptive information from the tail of the rat. © 1989.
Subjects
Extracellular single unit recording; Nociceptive neuron; Pain; Rat; Tail; Thalamus
Other Subjects
animal experiment; male; nerve cell; nociception; nonhuman; priority journal; rat; tail; thalamus; Action Potentials; Animal; Heat; Horseradish Peroxidase; Male; Nociceptors; Pain; Rats; Support, Non-U.S. Gov't; Tail; Thalamic Nuclei
Type
journal article
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