Process conditions on the morphology and encapsulation capacity of spray-dried media-milled cellulose powder
Date Issued
2015
Date
2015
Author(s)
Chang, Li-Wen
Abstract
In powder technology, control of particle morphology has received a lot of attention. The change of shapes has caused unprecedented chemical and physical properties that differ markedly from those of raw material. Spray dried technique is suggested to be a prospective way to produce various morphologies. Changing parameters of spray dryer is one of the strategy to control the morphology, including inlet temperature, solid concentration, gas flow rate, and so on. In this experiment, 3 different concentration (1% (w/w), 3% (w/w) and 5% (w/w)) of media milled cellulose and 4 different temperature (100℃, 115℃, 130℃ and 200℃) are chosen to spray dry. Physical properties and morphology of the cellulose spray dried powder would be analyzed. It shows that higher feed concentration produces larger spray dried particles. The particle size of 5% (w/w) feed concentration is two times as big as 1%(w/w). According to scanning electron micrograph, the spray dried cellulose powder at high concentration and high inlet temperature seems to form more spherical particle. It may relate to the evaporation rate, which affects the powder morphology, during drying. Higher inlet temperature and higher feed concentration result in faster evaporation, which leads to morphology variance. Also, the porosity of 5% feed concentration is the lowest, which infers to less open pore volume of the powder. Then, to assess the potential of media cellulose as a carrier, β-carotene is added into, according to the spray dried conditions mentioned above. It indicates that at 1% (w/w) feed concentration, the loading capacity is around 12-19%, while 5% (w/w) feed concentration is around 36-45%. The result implies that the particles at 130℃ inlet temperature and 5% (w/w) feed concentration show the highest loading capacity.
Subjects
cellulose
spray drying
morphology
encapsulation
Type
thesis
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