https://scholars.lib.ntu.edu.tw/handle/123456789/111286
標題: | AN INCREASED STANDARDISED MORTALITY RATIO FOR LIVER CANCER AMONG POLYVINYL CHLORIDE WORKERS IN TAIWAN | 作者: | WONG, RUEY-HONG CHEN, PAU-CHUNG |
關鍵字: | HEPATITIS-B VIRUS;VINYL-CHLORIDE;HEPATOCELLULAR-CARCINOMA;MONOMER WORKERS;P53 PROTEIN;INFECTION | 公開日期: | 2002 | 卷: | v.59 | 期: | n.6 | 起(迄)頁: | 405-409 | 來源出版物: | OCCUPATIONAL AND ENVIRONMENTAL MEDICINE | 摘要: | Aims: To determine the standardised mortality ratio (SMR) corresponding to different causes of death in workers from polyvinyl chloride polymerisation factories in Taiwan. Methods: Retrospective cohort study of workers from six polyvinyl chloride polymerisation factories in Taiwan. A total of 3293 male workers who had been employed for at least one year during the period 1 January 1950 to 31 December 1992, and were alive on 1 January 1985 were included for analysis. Using data acquired from Taiwan's National Mortality Registry, it was found that 144 of these workers died during the period 1985-97. The follow up rate was 99% with a total number of person-years at risk of 40 557.Results: SMR for all causes of death was 0.78, indicating a possible "healthy worker" effect. The SMR for liver cancer decreased with increasing age of first exposure to vinyl chloride monomer. This association was more prominent for workers who were first employed in the industry prior to 1970 (SMR 4.82). Medical records indicated that most liver cancers in this study were hepatocellular carcinoma.Conclusions: Polyvinyl chloride workers may experience a higher risk of developing liver cancer, particularly hepatocelluar carcinoma. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/80297 |
顯示於: | 環境與職業健康科學研究所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。