https://scholars.lib.ntu.edu.tw/handle/123456789/112686
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor | 流行病學所 | en |
dc.contributor.author | LU, SHENG-NAN | en |
dc.contributor.author | CHEN, HUI-CHI | en |
dc.contributor.author | WU, MEI-HUEI | en |
dc.contributor.author | YU, MING-LUNG | en |
dc.contributor.author | CHUANG, WAN-LONG | en |
dc.contributor.author | LU, CHIH-FENG | en |
dc.contributor.author | CHANG, WEN-YU | en |
dc.contributor.author | CHEN, CHIEN-JEN | en |
dc.creator | LU, SHENG-NAN;CHEN, HUI-CHI;WU, MEI-HUEI;YU, MING-LUNG;CHUANG, WAN-LONG;LU, CHIH-FENG;CHANG, WEN-YU;CHEN, CHIEN-JEN | en |
dc.creator | 盧勝男;陳慧祺;吳美惠;余明隆;莊萬龍;盧志崶;張文宇;陳建仁 | zh_TW |
dc.date | 1998 | en |
dc.date.accessioned | 2008-10-09T06:32:41Z | - |
dc.date.accessioned | 2018-06-29T17:59:39Z | - |
dc.date.available | 2008-10-09T06:32:41Z | - |
dc.date.available | 2018-06-29T17:59:39Z | - |
dc.date.issued | 1998 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/83461 | - |
dc.description.abstract | Background. According to our previous studies, Paisha Township in Penghu Islets is an endemic area for hepatitis B virus and hepatitis C virus (HCV) infection and for hepatocellular carcinoma. We conducted this study to understand the prevalence: of anti-HCV seropositivity among children in this area and to observe clinical manifestations of anti-HCV-positive children, Methods. In March, 1994, 1164 (93.6%) of 1243 students from all 6 kindergartens, 9 primary schools and 3 middle schools in Paisha Township participated in the screening for anti-HCV by enzyme immunoassay with second generation commercial kits (Abbott EIA 2.0). Anti-HCV tests were duplicated for the positive sera in 2 laboratories. All anti-HCV-positive children were followed annually for 2 years. Results. The prevalences of children from kindergartens (ages 3 to 6 years), primary schools (ages 7 to 12 years) and middle schools (ages 13 to 15 years) were 0% (0 of 229), 0.8% (5 of 617) and 1.9% (6 of 318), respectively. Initially the optic density (OD) values of anti-HCV were >2.0 in 4 cases (36%), between 1.0 and 2.0 in 2 cases, and <1.0 in the other 5 cases, None had sonographic parenchymal changes in the liver. In the 2-year follow-up of the anti-HCV-positive subjects, type 2a HCV-RNA persisted in 3 of 4 children with an OD of anti-HCV more than 2.0; 2 of them had 2 elevations of alanine transaminase values. Four of 7 children with an OD of 2.0 or less had a decrease in OD values in the follow-up examinations, and 2 of them became anti-HCV-negative. Conclusion. Only 36% (4 of 11) of anti-HCV-positive children had an OD of >2.0. Subjects with sequentially low OD might recover from chronic HCV infection without detectable HCV RNA and with normal alanine aminotransferase values. | en |
dc.language | en-us | en |
dc.language.iso | en_US | - |
dc.relation | PEDIATRIC INFECTIOUS DISEASE JOURNAL v.17 n.2 pp.142-145 | en |
dc.relation.ispartof | PEDIATRIC INFECTIOUS DISEASE JOURNAL | - |
dc.subject | hepatitis C virus | en |
dc.subject | epidemiology | en |
dc.subject | children | en |
dc.subject.classification | [SDGs]SDG3 | - |
dc.title | PREVALENCE AND MANIFESTATIONS OF HEPATITIS C SEROPOSITIVITY IN CHILDREN IN AN ENDEMIC AREA | en |
dc.type | journal article | en |
dc.relation.pages | 142-145 | - |
dc.relation.journalvolume | v.17 | - |
dc.relation.journalissue | n.2 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.languageiso639-1 | en_US | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
顯示於: | 流行病學與預防醫學研究所 |
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