https://scholars.lib.ntu.edu.tw/handle/123456789/113263
標題: | Outbreak of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Associated With Mebendazole and Metronidazole Use Among Filipino Laborers in Taiwan | 作者: | Chen, Kow-Tong Twu, Shiing-Jer Chang, Hong-Jen Lin, Ruey-Shiung |
公開日期: | 2003 | 起(迄)頁: | 489-492 | 來源出版物: | American Journal of Public Health | 摘要: | Objectives. This study sought to identify the risk factors associated with an outbreak of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) among Filipino laborers in Taiwan. Methods. Forty-six SJS/TEN patients were matched to 92 controls according to month of arrival in Taiwan, sex, and age. Results. The odds ratio for development of SJS/TEN was 9.5 (95% confidence interval [Cl]=3.9, 23.9) among workers who had used both metronidazole and mebendazole sometime in the preceding 6 weeks. In addition, a gradient increase in the occurrence of SJS/TEN was found with an increasing level of exposure to metronidazole. Conclusions. This outbreak highlights the risk of SJS/TEN resulting from the use of both metronidazole and mebendazole and the need for control measures. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/160571 | DOI: | 10.2105/AJPH.93.3.489 | SDG/關鍵字: | mebendazole; metronidazole; adult; amebiasis; article; dysentery; epidemic; ethnic group; female; human; major clinical study; male; prognosis; protozoal infection; race difference; risk factor; Stevens Johnson syndrome; Taiwan; toxic epidermal necrolysis |
顯示於: | 流行病學與預防醫學研究所 |
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