Repository logo
  • English
  • 中文
Log In
Have you forgotten your password?
  1. Home
  2. College of Life Science / 生命科學院
  3. Life Science / 生命科學系
  4. Evaluation of the neuronal network dynamics in anterior cingulate cortex using neuronal avalanche model
 
  • Details

Evaluation of the neuronal network dynamics in anterior cingulate cortex using neuronal avalanche model

Date Issued
2014
Date
2014
Author(s)
Wu, Jose Jiun-Shian
URI
http://ntur.lib.ntu.edu.tw//handle/246246/261688
Abstract
Cortical neurons display unique spatiotemporal patterns in signals processing to perform functions. Recent studies focus on the characteristics of the sufficient conditions in neuronal networks. The nLFPs exhibit a scale-free event size distribution, the neuronal avalanche, which has been proven in the cortex across species, including mice, rats, and humans, and may be used as an index of cortical excitability. However, it needs more investigation on the correlation between the neuronal avalanche and the cortical excitabilities. In this study, we hypothesize the neuronal avalanche could be taken as the index of the neuronal network excitability. The first aim of this study is to set up the analysis method of in vitro and in vivo recording. We measured nLFPs from multi-electrode recordings and approved the nLFPs in ACC and the S1 exhibit the distribution of the neuronal avalanche. The second aim of this study is focus on the nociceptive response in different level of the anesthesia, and we found in light anesthesia, the slope of the avalanche, α value, in ACC would be modulated by peripheral nociception. In the third part of this study, we try to evaluate the impact of the network excitability by the medial thalamic manipulation on ACC by traditional EEG analysis and the slope of the neuronal avalanche. We found that the α value could reflect network excitability and the thalamic manipulation. Final we conclude that the neuronal avalanche could be a tool for analyzing cortical network activity in physiological and pathological conditions through nLFPs to determine alterations in network dynamics.
Subjects
神經網路活性
神經雪崩模式
癲癇
痛覺傳遞
前扣帶腦迴皮質
Type
thesis
File(s)
Loading...
Thumbnail Image
Name

ntu-103-D95b41009-1.pdf

Size

23.32 KB

Format

Adobe PDF

Checksum

(MD5):075d6b890de8d16a511c0408fb628138

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

  • 請確認所上傳的全文是原創的內容,若該文件包含部分內容的版權非匯入者所有,或由第三方贊助與合作完成,請確認該版權所有者及第三方同意提供此授權。
    Please represent that the submission is your original work, and that you have the right to grant the rights to upload.
  • 若欲上傳已出版的全文電子檔,可使用Open policy finder網站查詢,以確認出版單位之版權政策。
    Please use Open policy finder to find a summary of permissions that are normally given as part of each publisher's copyright transfer agreement.
  • 網站簡介 (Quickstart Guide)
  • 使用手冊 (Instruction Manual)
  • 線上預約服務 (Booking Service)
  • 方案一:臺灣大學計算機中心帳號登入
    (With C&INC Email Account)
  • 方案二:ORCID帳號登入 (With ORCID)
  • 方案一:定期更新ORCID者,以ID匯入 (Search for identifier (ORCID))
  • 方案二:自行建檔 (Default mode Submission)
  • 方案三:學科館員協助匯入 (Email worklist to subject librarians)

Built with DSpace-CRIS software - Extension maintained and optimized by 4Science