https://scholars.lib.ntu.edu.tw/handle/123456789/138590
標題: | A Dual Selective Antitumor Agent and Fluorescence Probe: the Binary BMVC-Porphyrin Photosensitizer | 作者: | Kang, Chi-Chih Chen, Chin-Tin Cho, Chih-Chien Lin, Yu-Chen Chang, Cheng-Chung Chang, Ta-Chau |
關鍵字: | Cell death markers; Cytotoxicity; FRET; Photoinduced translocation; Singlet oxygen | 公開日期: | 2008 | 卷: | 3 | 期: | 5 | 起(迄)頁: | 725-728 | 來源出版物: | ChemMedChem | 摘要: | (Chemical Equation Presented) Two in one: o-2P-B (shown) generates singlet oxygen for photoinduced cytotoxicity that is highly selective for cancer cells without damaging normal cells. The required excitation wavelength is very well suited for tissue penetration in photodynamic therapy (PDT). The excellent contrast in cellular imaging of o-2B-P can be applied to monitor the pathway of PDT and serve as a cell death marker. ? 2008 Wiley-VCH Verlag GmbH & Co. KGaA. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/162653 | DOI: | 10.1002/cmdc.200700336 | SDG/關鍵字: | 3,6 bis(1 methyl 4 vinylpyridium)carbazole diiodide; 3,6-bis(1-methyl-4-vinylpyridium)carbazole diiodide; antineoplastic agent; carbazole derivative; fluorescent dye; photosensitizing agent; porphyrin; pyridinium derivative; article; chemistry; human; lung tumor; pathology; photochemotherapy; Antineoplastic Agents; Carbazoles; Fluorescent Dyes; Humans; Lung Neoplasms; Photochemotherapy; Photosensitizing Agents; Porphyrins; Pyridinium Compounds |
顯示於: | 生化科技學系 |
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