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  4. Examining the Association Between Quadriceps Strength and Cognitive Performance in the Elderly
 
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Examining the Association Between Quadriceps Strength and Cognitive Performance in the Elderly

Resource
Medicine (Baltimore), 94(32),
Journal
Medicine
Pages
e1335
Date Issued
2015
Date
2015
Author(s)
Chen, Wei-Liang
Peng, Tao-Chun
Sun, Yu-Shan
Yang, Hui-Fang
Liaw, Fang-Yih
Wu, Li-Wei
Chang, Yaw-Wen
Kao, Tung-Wei
DOI
10.1097/MD.0000000000001335
URI
http://ntur.lib.ntu.edu.tw//handle/246246/279833
Abstract
Emerging evidences showed impaired muscle strength was prevalent in older adults with mild cognition impairment or dementia. However, little was known about the role of quadriceps strength in the cognition decline among older population. The objective of our study was to investigate the relation between quadriceps strength and cognitive performance. Using data from the National Health and Nutrition Examination Survey (1999-2002), a total of 1799 participants aged 60 years were enrolled in the study. Every subject completed a household interview, digit symbol substitution test (DSST), physical performances, and a questionnaire regarding personal health. Estimation of relationship between quadriceps strength and cognition was using multiple linear regression and quartile-based analysis with an extended-model approach for covariates adjustment. In a model adjusted for demographics, chronic diseases, health behaviors, and levels of folate and vitamin B12, the level of quadriceps strength was significantly associated with the scores of DSST. The coefficient interpreted as change of DSST scores for each Newton increment in quadriceps strength comparing participants in the highest quartile of quadriceps strength to those in the lowest quartile was 5.003 (95% confidence interval, 2.725-7.281, P<0.001). The trends of incremental DSST score across increasing quartiles of quadriceps strength were statistically significant (all P for trend <0.001). Higher quadriceps strength was associated with better cognitive performance.
SDGs

[SDGs]SDG3

Other Subjects
cyanocobalamin; folic acid; adult; aged; alcohol consumption; Article; chronic disease; cognition; demography; digit symbol substitution test; female; folic acid blood level; health behavior; health survey; human; interview; major clinical study; male; mental performance; muscle strength; physical performance; priority journal; quadriceps femoris muscle; very elderly; middle aged; muscle strength; nutrition; physiology; regression analysis; Aged; Aged, 80 and over; Cognition; Female; Humans; Male; Middle Aged; Muscle Strength; Nutrition Surveys; Quadriceps Muscle; Regression Analysis

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