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  1. NTU Scholars
  2. 醫學院
  3. 臨床醫學研究所
Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/145631
Title: Role of Educational Status in Explaining the Association between Body Mass Index and Cognitive Function
Authors: Ho, Yi-Te
Kao, Tung-Wei
Peng, Tao-Chun
Liaw, Fang-Yih
Yang, Hui-Fang
Sun, Yu-Shan
Chang, Yaw-Wen
Chen, Wei-Liang
Issue Date: 2016
Start page/Pages: e2656
Source: Medicine 
Abstract: 
Preserving physical and cognitive function becomes an important issue as people age. A growing number of studies have found that the correlation between body mass index (BMI) and cognitive function changes in different age groups. It is obvious that higher educational status is linked to higher cognitive function in terms of numerous risk factors that influence cognitive function. This study aimed to investigate the interplay between obesity and cognitive function categorized by different educational status. ;This study included 5021 participants aged 20 to 59 years who completed 3 neurocognitive function tests, including a simple reaction time test (SRTT), a symbol digit substitution test (SDST), and a serial digit learning test (SDLT) as reported in the National Health and Nutrition Examination Survey (NHANES) III database. The associations between neurocognitive function and BMI were analyzed using multivariate linear regression while controlling for confounders. ;After adjusting for pertinent covariates in mode 3, the beta coefficients in the female participants with more than 12 years of education (interpreted as change of 3 neurocognitive function tests for each increment in BMI) comparing obesity groups to those with normal BMI were 16.2 (P < 0.001 for SRTT), 0.14 (P < 0.05 for SDST), and 0.9 (P < 0.05 for SDLT). Male participants with more than 12 years of education and female participants with fewer than 12 years of education demonstrated increased impairment as their BMI increased. However, this association was not significant after adjustments. ;Obese individuals had worse neurocognitive function than those of normal weight or overweight, especially in women with a high educational level.
URI: http://ntur.lib.ntu.edu.tw//handle/246246/279851
DOI: 10.1097/MD.0000000000002656
metadata.dc.subject.other: [SDGs]SDG3
adult; Article; body mass; clinical evaluation; cognition; cognition assessment; cognitive function test; controlled study; cross-sectional study; educational status; female; human; major clinical study; male; neurocognitive function test; obesity; priority journal; body mass; cognition; middle aged; nutrition; obesity; pathophysiology; physiology; psychology; psychometry; young adult; Adult; Body Mass Index; Cognition; Cross-Sectional Studies; Educational Status; Female; Humans; Male; Middle Aged; Nutrition Surveys; Obesity; Psychometrics; Young Adult
Appears in Collections:臨床醫學研究所

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臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

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開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

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