The Uncertainty and Hope Status of the Patients with Lung Cancer Participating in Clinical Trials
Date Issued
2015
Date
2015
Author(s)
Hsiao, Shu-Shien
Abstract
The purpose of this study was to explore the uncertainty and hope status of the patients with lung cancer participating in clinical trials. This study was a cross-sectional descriptive correlational design. A purposive sampling was used to recruit the patients at oncology ward, chest outpatient department, clinical trial ward, and chemotherapy rooms of medical center in northern Taiwan. Data were collected by using medical chart information, Mishel Uncertainty in Illness Scale (MUIS), Herth Hope Index (HHI). It was analyzed by using descriptive statistics, T test, one way-ANOVA, Pearson’s correlation and multiple regression analysis. A total of 100 subjects with lung cancer and enrolled in clinical trial were recruited and analyzed. The result of this study were as below, the mean score of the Uncertainty in Illness was 59.71 (59.71/125=47.77%); the related factors of uncertainty were years of education, occupational status, experiences of involved in clinical trials, self-awareness of disease severity, recent performance status, the length of participating this clinical trial, patient expectations of benefit from clinical trial, the understanding of clinical trial, the expected benefits of investigational product. The mean score of the hope was 29.10 (29.1/40=72.75%); the related factors of hope were years of education, occupational status, experiences of involved in clinical trials, self-awareness of disease severity, patient expectations of benefit from clinical trial, the understanding of clinical trial. The relation of uncertainty and hope status was significantly negative correlated and the uncertainty was a predictor of hope, which could explain 30% of the variance. The findings of this study could help practice nurse and clinical research nurse to understand the relation of uncertainty and hope status for patients of lung cancer who participating in clinical trials, afford information to clinical research nurse in caring clinical subjects, such as using empathy in explain inform consent form, understanding the uncertainty and hope, giving the emotion support and offer the individualized care. We expect the findings could be useful for the clinical research nurse and they could offer more sufficient help to patients. Future interventional studies should be designed in order to improve the uncertainty and hope status of patients and to enhance the quality of care for cancer patients.
Subjects
clinical trial
lung cancer
uncertainty
hope
clinical research nurse
SDGs
Type
thesis
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